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. 2000 May 15;149(4):761–766. doi: 10.1083/jcb.149.4.761

Figure 3.

Figure 3

The first step of the spindle orientation process in budding yeast. Microtubule binding proteins and cortical proteins are required. In the example shown, at the microtubule tip, Bim1p both increases microtubule dynamicity (arrows) and binds Kar9p at the cortex, followed by depolymerization (Lee et al. 2000; Korinek et al. 2000). In the subsequent step, the spindle is pulled (and pushed) into the bud neck through dynein-dependent forces.