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. 2000 May 15;149(4):825–834. doi: 10.1083/jcb.149.4.825

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© 2000 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Localization of MyoD in the stage 4 embryo. A drawing of the stage 4 embryo is shown in A. A DIC image of the primitive streak near Hensen's node is shown in B and the lateral region of the embryo in F. Cells ingressing into the primitive streak (ps) in the region of Hensen's node (hn) were intensely labeled with MyoD dendrimers (D). Less fluorescence was observed in more posterior regions of the streak (E). Groups of adjacent epiblast (e) and mesoderm cells (m; G) and mesoderm and hypoblast cells (h; H) also were labeled. Myosin dendrimers were not observed in the primitive streak near Hensen's node (C) or in more lateral regions of the embryo (I). Bar, 9 μm.