Table III.
TCR variable-region restriction of MART-1-reactive clones of various avidities
| Mart Clone | TCR Vα | TCR Vβ | Clone Avidity/Affinity (IFN-γ/CD8 independence) |
|---|---|---|---|
| DMF4 | 35 | 10-3 | Medium/Medium |
| DMF5 | 12-2 | 6-4 | High/High |
| JKF6 | 12-2 | 28 | High/High |
| #17 | 12-2 | 11-2 | Medium/High |
| M5 | 12-2 | 6-5 | High/High |
| M7 | 12-2 | 19 | Low/Low |
| M9a | 12-3 | 4-1 | Low/Low |
| M20a | 12-3 | 4-1 | Low/Low |
Clone M9 and M20 are the same clone, derived from the same patient.