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. 2000 Feb 7;148(3):405–416. doi: 10.1083/jcb.148.3.405

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© 2000 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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CDC31 and centrin from Chlamydomonas reinhardtii define two divergent subfamilies. Note that human and murine CEN3 and CDC31 belong to the same subfamily, whereas HsCEN1, HsCEN2, and centrin from Chlamydomonas belong to the other subfamily. Accession numbers are indicated for the S. pombe centrin gene sequence, which has been found in the genome sequencing project and for the two divergent Giardia genes. Bar, mutation frequency.