Figure 2.

Levels of the expression of LMP1 correlate with lymphoid pathologies. Immunoblots were prepared with total protein tissue lysate (200 μg) and 50 μg of protein lysate from the B95–8 EBV-positive lymphoid cell line (lane 1) and reacted with the CS1–4 mouse monoclonal antibody. A spontaneous lymphoma was obtained from a 2-year-old LMP1-negative littermate (lane 2). Lanes 3–5 are lymphoma tissues; lanes 6–7 are lymphoid hyperplasia; lanes 8–10 are normal lymphoid tissues. Lanes 3–10 are transgenic splenic tissues from lineage 3.