Figure 3.

The Distribution of mRNA Half-Lives of the Whole Genome Compared with Subsets of Transcripts with Specific Sequence Features.

(A) to (C) The proportion of transcripts in each mRNA half-life category for the whole-genome set and for subsets, including transcripts that are (A) known miRNA targets; (B) contain no introns (light blue), has one or more splice variant/s that does not have an intron (black), or has a one or more splice variants that contain an intron in all the splice variants (i.e., always intron containing [red]) (C); contain a 3′ UTR >300 bp, contain a 3′ UTR intron, has one or more splice variants that contain a retained 3′ UTR, or has one or more slice variants that never contains a 3′ UTR intron in all the splice variants.

(D) Transcripts that had 0 h signal intensities of <100, >100 to < 1000, and >1000. The cumulative percentage plots graphically display how the mRNA half-lives are distributed in each category. The D-value represents the distance between the distributions and was used to calculate the Kolmogorov-Smirnov statistic [p(same)] to determine if there was a statistically significant difference (asterisk) between each subset compared with the genome. The number of genes in each data set is indicated in parentheses.