Figure 1.

Replication of VZV in MeWo cells and thymus/liver implants. (A) MeWo cells were inoculated on day 0 with an infected-cell inoculum of either ROka (□), ROka47SR (○), ROka66S (•), or ROka47S (■). Aliquots were harvested daily for 4 days, and infectious foci were determined by titration on Vero cell monolayers. (B) Thymus/liver implants were inoculated with VZV-infected MRC-5 cells on day 0 (inoculum sizes shown on y-axis) and harvested weekly. T cell suspensions were prepared and titrated in the infectious foci assay. Each point represents the mean of at least three implants from two separate experiments.