Effects of CRF1 receptor antagonism on pCREB expression in the LA, BLA and CeA nuclei at different contextual fear conditioning intervals. A, Digital images representing the effects of homecage (HC), vehicle (Veh), and DMP696 (10 mg/kg, po) treatment on pCREB expression in the LA, BLA nucleus, and CeA 0.25 h after exposure to contextual fear conditioning. B, Effects of DMP696 (10 mg/kg, po) on LA pCREB expression at different post-contextual fear conditioning intervals (*P<0.01, homecage control significantly difference from vehicle but not DMP696 groups at 0.25, 1, and 4 h intervals). C, Effects of DMP696 (10 mg/kg, po) on BLA pCREB expression at different post-contextual fear conditioning intervals (*P<0.01, homecage control significantly difference from vehicle but not DMP696 groups at 0.25, 1, and 4 h intervals). D, Effects of DMP696 (10 mg/kg, po) on CeA pCREB expression at different post-contextual fear conditioning intervals (*P<0.01, homecage control significantly difference from vehicle and DMP696 groups at 0.25, 1, and 4 h intervals).