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. Author manuscript; available in PMC: 2008 Oct 26.
Published in final edited form as: Neuroscience. 2007 Jul 20;149(2):338–349. doi: 10.1016/j.neuroscience.2007.07.017

Fig. 7.

Fig. 7

Pretreatment with protein kinase C inhibitor (calphostin C) but not protein kinase A inhibitor (H-89) prevents KAR activation-induced inhibition of mIPSCs. A: mIPSCs were recorded in the presence of 1 μM calphostin C and calphostin C together with 1 μM KA. B: mIPSCs were recorded in the presence of 0.5 μM H-89 and H-89 together with 1 μM KA. C and D: the cumulative distributions of the inter-mIPSC intervals and amplitude distributions of mIPSCs obtained from the same neuron as in A. KA had no effect on inter-event interval (left) and mIPSCs amplitude (right) distribution curves in the presence of calphostin C (P > 0.5). E: summary bar graph shows that KA had no effect on mIPSCs frequency in the presence of 0.5 μM staurosporine and calphostin C but not in the presence of H-89. F: summary bar graph shows that KA had no effect on mIPSCs amplitude in the presence of staurosporine, calphostin C and H-89. * P < 0.05.