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. Author manuscript; available in PMC: 2008 Jan 7.
Published in final edited form as: Biochim Biophys Acta. 2007 Oct 9;1773(12):1793–1800. doi: 10.1016/j.bbamcr.2007.09.008

Figure 1. Mutation of the Rit effector loop alters neurite outgrowth ability.

Figure 1

(A) Sequence alignment of the effector domains from several Ras family GTPases. (B) PC6 cells were transiently transfected, subjected to G418 (400 μg/ml) selection for 3 days, fixed and stained with FITC-phalloidin to label actin filaments. Representative fluorescent micrographs from random fields are presented. (C) The percentage of neurite-bearing cells was calculated at day 3 and is presented relative to RitL79 (100%) as means ± standard error from three independent experiments.

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