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Intracellular Localization of Plakophilin 1 and Its Fragments
| Desmosome | Nucleus | Cytoplasm | IF- associated | Actin- associated | |
|---|---|---|---|---|---|
| PKP1 head | ++ | ++ | (+) | (+) | − |
| PKP1 head ΔC1 | ++ | + | (+) | (+) | − |
| PKP1 head ΔC2 | + | ++ | + | + | − |
| PKP1 head ΔN1 | ++ | + | (+) | (+) | − |
| PKP1 head ΔN2 | ++ | ++ | + | (+) | − |
| PKP1 headless | n.d. | (+) | ++ | − | ++ |
| PKP1 arm repeat | n.d. | (+) | ++ | − | ++ |
| PKP1 arm repeat ΔENCMC | − | (+) | ++ | − | − |
