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. 2000 Apr 3;149(1):153–166. doi: 10.1083/jcb.149.1.153

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© 2000 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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The amino acid sequence of the Orbit protein. A basic domain with a predicted pI of 11.0 flanked by short acidic regions of pI 4.1 and 4.3, respectively, are shown in boxes. The sequence shows extensive homology with a human putative proteins, KIAA0622 and KIAA0627, and related proteins from C. elegans, R107.6 and ZC84.3, which are underlined. Consensus sites for phosphorylation by p34^cdc2 are shaded. The possible GTP-binding motif, GGGTGTG, identical to the GTP binding site in the FtsZ protein of E. coli, and NKLD, which matches a consensus motif for GTP binding in the GTPase family, are indicated by double underlining. These sequence data are available from GenBank/EMBL/DDBJ under accession number AB031048.