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Upregulation of CD107a cell surface expression in response to tumor stimulation in TIL 2098. 1 × 105 TIL 2098 T cells were co-cultured with 1 × 105 allogeneic 888mel tumor cells (A) or 1 × 105 autologous 2098mel tumor cells (B) for 16 hours. CD107a expression as well as TRBV2 and TRBV27 expression detected by corresponding TCR VB22 antibody and VB12 antibody respectively in TIL 2098 T cells was analyzed by FACS.
