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. 2000 Aug 7;150(3):499–512. doi: 10.1083/jcb.150.3.499

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© 2000 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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KRP₁₈₀ is required to maintain spindle shape in prometaphase sea urchin embryos. Spindle pole-to-pole distances were measured over time in control and anti-KRP₁₈₀ antibody injected embryos. Time 0 in each graph represents NEBD and the final time point in each graph indicates the completion of cytokinesis. Bold type numbers 1 and 2 indicate two distinct phases of anaphase B spindle elongation. The arrowhead indicates the transition from the first slow phase of spindle pole elongation to the second fast phase.