Table 1.
LPC | Total LPC concentration giving 50% fusion inhibition | Membrane concentration of LPC giving 50% fusion inhibition |
---|---|---|
μM | % | |
Lauroyl | 240 ± 50 | 4.1 ± 0.5 |
Myristoyl | 23 ± 2 | 5.8 ± 0.5 |
Palmitoyl | 6.5 ± 1 | 8.7 ± 2 |
Stearoyl | 4.1 ± 2 | 9.9 ± 2 |
The total LPC concentration in the medium giving 50% of fusion inhibition was calculated from the graph in Fig. 2. The amount of LPC incorporated in the membrane, and thus the membrane concentration of LPC giving 50% of inhibition, were calculated as indicated in Materials and Methods.