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Effect of bub1 Loss of Function on the Fidelity of Minichromosome Transmission through Mitosis
| Strain | Background | Chromosome loss per division | Fold increase in loss rate | |||||
|---|---|---|---|---|---|---|---|---|
| % | ||||||||
| 530-kb linear | 499 | Wild-type | <0.05 (0 out of 2,187) | 1 | ||||
| minichromosome | 502 | Δbub1 | 3.5 (81 out of 2,302) | 70 | ||||
| Ch16Δbub1 | ||||||||
| 30-kb circular | 14 | Wild-type | 1.6 (46 out of 2,875) | 1 | ||||
| minichromosome | 428 | Δbub1 | 20.4 (470 out of 2,302) | 12.75 | ||||
| CM3112 |
