Table 4.
Quantitative Comparison of MT Number and Cross-sectional Area of Axons
Experiments | #1 | #2 | ||||
---|---|---|---|---|---|---|
MT number | Area of axons | n | MT number | Area of axons | n | |
tau+/+map1b+/+ | 7.8 ± 0.4 | 0.091 ± 0.006 | 223 | 6.7 ± 0.2 | 0.068 ± 0.003 | 322 |
tau−/−map1b+/+ | 5.7 ± 0.2 | 0.089 ± 0.005 | 227 | 6.8 ± 0.3 | 0.082 ± 0.005 | 239 |
tau+/+map1b−/− | 5.6 ± 0.2 | 0.060 ± 0.003 | 425 | 5.2 ± 0.2 | 0.067 ± 0.003 | 480 |
tau−/−map1b−/− | 2.4 ± 0.1 | 0.035 ± 0.002 | 710 | 2.6 ± 0.1 | 0.036 ± 0.002 | 663 |
MT number and area of axons (μm2) per axon were measured directly on electron-microscopic micrographs of anterior commissure sections in two independent experiments (#1 and #2). The mice were killed at postnatal week 4. The means ± SEM are shown. n, Number of axons examined.