Table 1.

Sequences of the mutated 119 bp fragments

119 (original sequence)	5′-ACGATGGGGACCGTTTGTGCCACTCGGGAGAAGTGGTGGGTGG GTACGCTGCTCCGTCGTGCGTGCGTGA GTGCCGGAACCTGAGCTCGGGAGACCCTCCGGAGAGACAGAATGAGTGA_3′
119.S1	5′-ACGATGGGGACCGTTTGTGCCAAGATGGAGAAGTGGTGGGTGG GTACGCTGCTCCGTCGTGCGTGCGTGA GTGCCGGAACCTGAGCTC GGGAGACCCTCCGGAGAGACAGAATGAGTGA-3′
119.S2	5′-ACGATGGGGACCGTTTGTGCCAAGATTTCTAAGTGGTGGGTGG GTACGCTGCTCCGTCGTGCTGCGTGAG TGCCGGAACCTGAGCTC GGGAGACCCTCCGGAGAGACAGAATGAGTGA-3′
119.S3	5′-ACGATGGGGACCGTTTGTGCCAAGATTTCTAAGTGGTGGGTGG GTACGCTGCTCCGTCGTGCGTGCGTGA GTGCCGGAACCTGAGAGA TGGAGACCCTCCGGAGAGACAGAATGAGTGA-3′
119.S4	5′-ACGATGGGGACCGTTTGTGCCAAGATTTCTAAGTGGTGGGTGG GTACGCTGCTCCGTCGTGCGTGCGTGAGTGCCGGAACCTGAGAGAT TTCTACCCTCCGGAGAGACAGAATGA GTGA-3′

Conspicuous sequence elements are depicted in bold letters, introduced mutations are underlined.