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. 2008 Jan 16;3(1):e1433. doi: 10.1371/journal.pone.0001433

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Marella et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Rotenone exposure was carried out as described in Figure 2. Each rat was placed in a round bucket after apomorphine administration and the movement was video-taped for 30 min. Data were analyzed for the four groups; Ctl (n = 3), Ctl+Rot (n = 14), NDI1 (n = 5) and NDI1+Rot (n = 20). n = number of animals. A: Speed of movement of rats was calculated as the number of full turns per minute. B: The number of rats exhibiting fully lateralized turning in either direction was counted. Histograms represent percentage of animals turning only in one direction. (*: p<0.05; **: p<0.01). All values are presented with standard deviation.