TABLE 4.

Comparison of demographic, culture, and clinical data in the current series and two previous primary case series

Parameter	Value from:
	Reference 136		Reference 177		Current review
	Necrobacillosisa	Lemierre's syndrome	Necrobacillosisa	Lemierre's syndrome	Necrobacillosisa	Lemierre's syndrome
No. of cases	44	29	24	15	251	222
Age range (yr)	0.1-65	9-32	0.6-46	14-31	0.2-73	0.7-70
Median age (yr)		22.6 (male), 20.4 (female)	17	19	18	19
% Male	67	66	67	67	55	57
% of cases with:
F. necrophorum	100b	100b	100b	100b	100b	68
Any Fusobacterium sp.	100	100b	100b	100b	100b	86
F. necrophorum or Fusobacterium sp. in mixed culture	2	3	33	40-53	12	12
Other organism without fusobacteria	NAb,c	NAb	NAb	NAb	NAb	8
IJV thrombosis	4.5	3.4	NR	NR	37	59
Metastases	75	97	63	80	73	100
Lung lesions	55	79	54	80	60	92
Empyema	NRd	NR	17	27	12	17
Septic arthritis	18	21	0	0	12	11
Osteomyelitis	7	3.4	0	0	7	5.4
Muscle involvement	0	0	0	0	5	7.2
Skin involvement	0	0	0	0	2.3	3.1
Liver abscess	2.3	3.4	4.2	0	6	4.0
Meningitis	9	3.4	4.2	0	8	1.4
Cerebral abscess	2.3	3.4	0	0	3.6	1.8
Septic shock	NR	NR	NR	NR	NR	7
Renal failure	2.3	3.4	NR	NR	NR	2
Disseminated intravascular coagulation	7	10	29	47	NR	4
Antibiotic duration	NR	Mean, 6 wk	0-58 days (median, 17 days)	0-35 days (median, 18 days)	NR	NR
% Mortality	4.5	3.4	0	0	7	4.9

^aExcludes cases arising outside the head and neck.

^bDetermined by entry criteria used by authors.

^cNA, not applicable.

^dNR, not recorded.