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. 2007 Jul 26;176(11):1090–1097. doi: 10.1164/rccm.200702-215OC

TABLE 1.

OVERVIEW OF CHARACTERISTICS OF ASSAYS USED IN SPECIFIC IgE AND IgG ANTI–HEXAMETHYLENE DIISOCYANATE ANALYSES

Conjugate Source* Carrier Phase Isocyanate Test System
HDI–ImmunoCAP Phadia ImmunoCAP (as solid phase) Done by manufacturers ImmunoCAP assay
HDIL–HSA IRAS HSA Liquid EIA
HDIV–HSA Yale HSA Vapor EIA
N3300–HSA Yale HSA Liquid EIA
N100–HSA Yale HSA Liquid EIA

Definition of abbreviations: EIA = enzyme immunoassay; HDI = hexamethylene diisocyanate; HDIL–HSA = HDI–HSA liquid phase; HDIV–HSA = HDI–HSA vapor phase; HSA = human serum albumin; IRAS = Institute for Risk Assessment Sciences.

Source where the conjugate was prepared, technical details, and system in which the conjugate was used are shown.

*

Sources: Phadia, Sweden; IRAS, The Netherlands; Yale School of Medicine, Connecticut.

Phase of the isocyanate mixture during reaction.