TABLE 3.
Office Workers (n = 50) | Spray Painters (n = 241) | Others (n = 290) | |
---|---|---|---|
Respiratory symptoms, % | |||
Chronic cough | 2.0 | 15.4† | 13.6† |
Chronic phlegm | 4.0 | 13.3 | 10.8 |
Shortness of breath | 4.0 | 8.8 | 8.4 |
Wheezing | 12.0 | 29.1‡ | 22.6† |
Frequent wheezing (>1 wk) | 4.0 | 12.5‡§ | 4.9 |
Shortness of breath during wheezing | 4.0 | 16.2† | 10.5 |
Chest tightness | 14.0 | 18.3 | 14.4 |
Chest tightness before start work | 10.0 | 8.8 | 7.1 |
Clusters of symptoms, % | |||
COPD-like symptoms | 8.0 | 26.1‡ | 20.6† |
Asthmalike symptoms | 14.0 | 33.6‡ | 28.0‡ |
Work-related symptoms, % | |||
Work-related rhinitis | 14.3 | 19.8 | 15.0 |
Work-related chest tightness | 2.0 | 8.3 | 4.0 |
Work-related conjunctivitis | 12.0 | 16.0 | 10.4 |
Positive serology, % | |||
Atopy (Phadiatop) | 44.0 | 33.6‡‖ | 37.6 |
Specific IgE | |||
HDI–ImmunoCAP | 0 | 2.1 | 1.0 |
HDIL–HSA | 0 | 2.9 | 3.5 |
HDIV–HSA | 0 | 0.4 | 0.7 |
N3300–HSA | 0 | 2.1 | 1.0 |
N100–HSA | 0 | 4.2 | 2.1 |
Specific IgG | |||
HDI–ImmunoCAP | 4.0 | 9.5 | 7.2 |
HDIL–HSA | 32.0 | 50.4‡ | 41.5 |
HDIV–HSA | 2.0 | 20.0‡¶ | 9.3 |
N3300–HSA | 10.0 | 23.3 | 15.1 |
N100–HSA | 4.0 | 34.6‡ | 21.5‡ |
Definition of abbreviations: COPD = chronic obstructive pulmonary disease; HDI = hexamethylene diisocyanate; HDIL–HSA = HDI–HSA liquid phase; HDIV–HSA = HDI–HSA vapor phase; HSA = human serum albumin.
Atopy and specific IgE and IgG sensitization against HDI.
P < 0.10; significantly different from “office workers” category after adjustment for atopy, current smoking, age, and sex.
P < 0.05; significantly different from “office workers” category after adjustment for atopy, current smoking, age, and sex.
Adjusted for atopy, current smoking, and sex.
Adjusted for current smoking, age, and sex.
Adjusted for for atopy, current smoking, and age.