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. 2007 Jul 26;176(11):1090–1097. doi: 10.1164/rccm.200702-215OC

TABLE 5.

ASSOCIATION BETWEEN RESPIRATORY SYMPTOMS AND SPECIFIC IgE AND IgG SENSITIZATION AND EXPOSURE

PR (95% CI)
Symptoms
 Asthmalike symptoms 1.2 (1.01.5)*
 COPD-like symptoms 1.3 (1.0–1.7)*
 Work-related chest tightness 2.0 (1.0–3.9)*
 Work-related rhinitis 1.3 (0.9–1.7)
 Work-related conjunctivitis 1.5 (1.0–2.1)*
Specific IgE
 HDI–ImmunoCAP 2.2 (0.6–8.2)
 HDIL–HSA 1.4 (0.7–3.0)
 HDIV–HSA 0.6 (0.1–3.9)
 N3300–HSA 1.8 (0.5–7.2)
 N100–HSA 3.0 (1.1–8.4)*§
Specific IgG
 HDI–ImmunoCAP 1.2 (0.71.9)
 HDIL–HSA 1.2 (1.1–1.4)*
 HDIV–HSA 2.2 (1.5–3.4)*
 N3300–HSA 1.6 (1.2–2.2)*
 N100–HSA 2.0 (1.5–2.6)*

Definition of abbreviations: COPD = chronic obstructive pulmonary disease; HDI = hexamethylene diisocyanate; HDIL–HSA = HDI–HSA liquid phase; HDIV–HSA = HDI–HSA vapor phase; HSA = human serum albumin.

Shown are prevalence ratios (95% CI) for an interquartile range increase in exposure adjusted for age, sex, smoking, and atopy.

*

P ⩽ 0.05.

Adjusted for age, smoking, and atopy.

Adjusted for age, smoking, and sex.

§

Adjusted for age, sex, and atopy.