TABLE 2.

ALLELE AND DIPLOTYPE FREQUENCIES IN THE STUDY POPULATION

	Allele Frequency			Diplotype Frequencies rs4803457 C>T − rs1800469 C>T
	C	T	PHWE*	CC	CT	TC	TT	R2h†
Overall sample (n = 3,023)
rs4803457	0.57	0.43	0.24
				0.567	0.004	0.072	0.357	0.938
rs1800469 (C-509T)	0.64	0.36	0.99
Non-Hispanic white (n = 2,096)
rs4803457	0.60	0.40	0.17
				0.592	0.005	0.081	0.322	0.938
rs1800469 (C-509T)	0.67	0.33	0.88
Hispanic white (n = 927)
rs4803457	0.51	0.49	0.61
				0.509	0.004	0.052	0.435	0.939
rs1800469 (C-509T)	0.56	0.44	0.22

^*P values for Hardy-Weinberg equilibrium (from PROC Allele in SAS).

^†R²_h, or coefficient of determination, is a measure that describes the extent of the haplotype diversity accounted for by rs4803457 C>T and rs1800469 C>T single-nucleotide polymorphisms.