Figure 5.
Differential effects of high and low doses of 6.3G9 on bronchoalveolar lavage (BAL) fluid protein concentrations. (A) Nonirradiated mice were treated for 4 weeks with control monoclonal antibody (mAb) or the indicated doses of 6.3G9, followed by measurement of concentrations of the indicated proteins in BAL fluid (n = 5–8 per group). (B and C) Irradiated mice were treated for 12 or 16 weeks with control mAb or indicated doses of 6.3G9, beginning 16 weeks after irradiation. The concentrations of the indicated proteins in BAL fluid obtained from these mice were then measured. *P < 0.05, **P < 0.01, compared with control antibody treatment (n = 7–13 per group).