TABLE 5.
ODDS RATIOS FOR ATOPY ALONE AND ATOPIC ASTHMA COMPARED WITH CONTROL SUBJECTS WITHOUT ATOPY AMONG FARM WOMEN IN THE AGRICULTURAL HEALTH STUDY
| Patients with Asthma
|
||||||
|---|---|---|---|---|---|---|
| Control Subjects (n = 21,803)
|
Atopy Alone (n = 3,086)
|
Atopic Asthma (n = 282)
|
P Value for Difference§ | |||
| Exposure* | n (%)† | n (%)† | OR (95% CI)‡ | n (%)† | OR (95% CI)‡ | |
| Herbicides | ||||||
| 2,4-d | 3,237 (15) | 477 (16) | 1.20 (1.08–1.34) | 52 (19) | 1.57 (1.15–2.15) | 0.11 |
| Glyphosate | 7,243 (34) | 1,174 (39) | 1.31 (1.21–1.42) | 106 (39) | 1.35 (1.05–1.73) | 0.81 |
| Insecticides | ||||||
| Carbaryl | 6,604 (31) | 1,119 (37) | 1.36 (1.26–1.48) | 106 (38) | 1.46 (1.14–1.87) | 0.58 |
| Coumaphos | 281 (1) | 37 (1) | 1.00 (0.71–1.42) | 7 (3) | 2.16 (1.01–4.64) | 0.07 |
| DDT | 761 (4) | 148 (5) | 1.60 (1.33–1.93) | 16 (6) | 1.91 (1.13–3.24) | 0.53 |
| Malathion | 4,273 (20) | 698 (23) | 1.28 (1.17–1.41) | 76 (28) | 1.65 (1.26–2.16) | 0.08 |
| Parathion | 195 (1) | 44 (1) | 1.68 (1.21–2.34) | 7 (3) | 3.15 (1.46–6.79) | 0.13 |
| Permethrin (animals) | 758 (4) | 132 (4) | 1.36 (1.12–1.64) | 15 (6) | 1.77 (1.04–3.02) | 0.34 |
| Phorate | 421 (2) | 56 (2) | 1.07 (0.81–1.42) | 10 (4) | 2.06 (1.08–3.93) | 0.06 |
| Fungicides | ||||||
| Metalaxyl | 299 (1) | 64 (2) | 1.36 (1.03–1.80) | 10 (4) | 2.73 (1.41–5.29) | 0.05 |
Definition of abbreviations: CI = confidence interval; OR = odds ratio.
*
Only those pesticides significant in the original models (Table 2) are presented here.
†
Percentages based on numbers responding to the question; missing values are not included.
‡
ORs adjusted for age, state, smoking status, body mass index, and “grew up on farm.”
§
P value for the test formally comparing the ORs for atopic and nonatopic asthma.