Figure 2. Expression of genes implicated in mitochondrial biogenesis and in mtDNA replication.
mRNA levels of mitochondrial biogenesis (A) and mtDNA replication (B) genes, determined by quantitative RT-PCR, in the gastrocnemius muscle of the mice after 4 and 16 weeks of the SD or HFHSD (n = 6). Results are expressed as fold change versus the SD diet set to 1 unit (dotted line). *P < 0.05.