Figure 5.

Comparison of the amino acid sequence in the active site of γECS from different organisms. The derived amino acid sequence of γECS from Trypanosoma brucei (T. brucei), Arabidopsis thaliana (A. thalia), Rattus norvegii (R. norveg), and Saccharomyces cerevisiae (S. cerevi) corresponds to the active site prediction of Lueder and Phillips (35). Identical amino acids are shaded, the potential calmodulin-dependent kinase motif on the A. thaliana sequence is underlined, and the putative active-site cysteine is marked with an asterisk. Numbers to the left indicate the amino acid position on each sequence.