Figure 1.

(A) The human PNR cDNA and predicted amino acid sequences. An in-frame stop codon preceding the initiation methionine codon is underlined. DBD and LBD regions are boxed. There are some sequence ambiguities in the 3′ untranslated region. A potential poly(A)⁺ signal (AATAAA) is double-underlined. Intron positions are indicated by ▿ (see Table 1 for details). (B) Comparison of human PNR (hPNR) with nematode F56E3.4 and other nuclear receptors. The % identity is indicated in the aligned sequences for the DBDs and LBDs. (C) Southern blot analysis using the LBD region of the human PNR cDNA as a probe. Distinct bands were dectected in all lanes.