Table 1.
Parameter values used in the simulations
| Parameter | H+ ATPase | Na+ ATPase |
|---|---|---|
| Ion diffusion constant (DI), nm2⋅s−1 | 9.3 × 109 | 1.0 × 109 |
| Diffusion constant of rotor (Dr), s−1 | 1.0 × 104 | 1.0 × 104 |
| Dielectric constant of stator (ɛs) | 4.0 | 4.0 |
| Bilayer viscosity (η), poise | 10 | 10 |
| Radius of rotor (R), nm | 3 | 3 |
| Ion conductivity of channel, M−1⋅s−1 | 1.2 × 1011 | 1.2 × 107 |
| pKa of rotor sites | 7.1 | 3.5 |
| Concentration of periplasmic side | pHp = 7.0 | [Na+]p = 1.0 mM |
| Concentration of cytoplasmic side | pHC = 7.4 | [Na+]C = 1.0 mM |
| Membrane potential (Δψ) | 175 mV = 7 kBT | 200 mV = 8.0 kBT |