Figure 1.
Transgenic SP-A(−/−) mice, mycoplasma-resistant C57BL, and susceptible C3H mice were infected intranasally with 105 cfu of M. pulmonis. Mice were euthanized at 1, 2, 3, or 7 days p.i., and cfu numbers (total recoverable mycoplasmas) were determined on whole-lung homogenates. cfu are graphed on a logarithmic scale. ∗, significant difference from the other two remaining groups at each time point, P < 0.05, #, significant difference from the other two groups at this time point, P < 0.05. Results of quantitative cultures are mean ± SE; n ≥18.