C57BL iNOS(−/−) and control C57BL iNOS(+/+) mice were infected intranasally with 1.5 × 107 cfu per ml M. pulmonis. Mice were euthanized at 1, 2, 3, or 7 days p.i., and cfu numbers (total recoverable mycoplasmas) were determined on whole-lung homogenates. ∗, significant difference between control and experimental conditions at each time point, P < 0.05. Results of quantitative cultures are mean ± SE; n ≥ 18.