Table 1.
Demographic and Neuropsychological Data for All Subjects
| Measure | SM046 | NC | LTL | RTL | Statistic | P |
|---|---|---|---|---|---|---|
| Demographics | ||||||
| Age | 35 | 37 ± 11.2 | 39 ± 9.9 | 38 ± 9.4 | F < 1 | >0.6 |
| Gender | F | 12F/8M | 7F/4M | 4F/5M | χ2 = 1.5 | >0.4 |
| Education | 12 | — | 14 ± 1.8 | 14 ± 1.8 | t < 1 | >0.6 |
| Handedness | R | — | 8R/3L | 8R/1L | χ2 < 1 | >0.5 |
| Years Post-Surgery | — | — | 4.6 ± 5.1 | 6.8 ± 6.2 | t = 0.5 | >0.6 |
| Olfactory Function | ||||||
| UPSIT | 32 | 34.2 ± 3.3 | 31.4 ± 4.5 | 33.0 ± 2.6 | F = 2.4 | 0.1 |
| Neuropsychological Data | ||||||
| AVLT d′ | 2.87 | — | 2.97 ± 0.92 | 3.3 ± 0.6 | t = 1.2 | 0.24 |
| AVLT C | 0.43 | — | 0.06 ± 0.3 | 0.09 ± 0.11 | t < 1 | >0.7 |
| VIQ | 86 | — | 94 ± 9.0 | 100 ± 13.8 | t = 2.0 | 0.062 |
| PIQ | 90 | — | 99 ± 13.7 | 104 ± 16.0 | t < 1 | >0.5 |
| VRT Correct | 5 | — | 7.9 ± 1.7 | 6.8 ± 1.8 | t = 1.1 | 0.3 |
| VRT Errors | 10 | — | 3.3 ± 3.3 | 4.8 ± 3.9 | t < 1 | >0.3 |
| CFT | 13.5 | — | 18 ± 6.2 | 16 ± 6.5 | t < 1 | >0.3 |
| Aphasia | N | — | 9N/2Y | 9N | χ2 = 1.6 | >0.2 |
| WCST Categories | — | — | 5.3 ± 1.3 | 5.1 ± 1.2 | t < 1 | >0.9 |
| COWA | 25 | — | 38 ± 13.2 | 37 ± 10.0 | t < 1 | >0.7 |
| BDI | — | — | 9.0 ± 7.5 | 8.6 ± 8.4 | t < 1 | >0.8 |
| Neuroanatomical Data | ||||||
| Left Amyg Volume | 0 | — | 744 ± 175 | 1908 ± 129 | t = 5.1 | 0.0001 |
| Right Amyg Volume | 0 | — | 1602 ± 97 | 934 ± 168 | t = 3.6 | 0.002 |
| Left HC Volume | 2576 | — | 1398 ± 254 | 3907 ± 218 | t = 7.3 | 0.0001 |
| Right HC Volume | 2893 | — | 4156 ± 154 | 1530 ± 268 | t = 8.9 | 0.0001 |
(NC) Normal control group; (LTL) left temporal lobectomy group; (RTL) right temporal lobectomy group; Education is reported in years; Handedness was assessed with the Edinburgh Handedness Inventory; (BDI) Beck Depression Inventory; (VIQ) WAIS-R Verbal Scale IQ; (PIQ) WAIS-R Performance Scale IQ; (AVLT d′) Auditory-Verbal Learning Test discriminability score; (AVLT C′) Auditory-Verbal Learning Test bias score; (VRT) Visual Retention Test, (Correct) number correct of 10, (Errors) number of errors committed; (CFT) Complex Figure Test, 30 min recall; (Aphasia) subjects classified as N = None, Y = Mild/moderate aphasia; (WCST Categories) Wisconsin Card Sort Test, number of categories achieved; (COWA) Controlled Oral Word Association (no. of words generated for the letters C, F, and L); Right and left amygdala volume as determined from MRI images (in mm3); Right and left hippocampal volume; Years Post-Surgery (time since temporal lobectomy). Statistics were performed comparing temporal lobectomy groups and normal controls (those measures on which F-ratios are reported) or comparing right and left temporal lobectomy groups (those measures on which t-tests are reported). Data from patient SM046 were not included in these analyses. Data are reported as mean ± standard error of the mean.