. 2003 Sep;10(5):355–362. doi: 10.1101/lm.60803

Table 4.

Comparison of the Efficacy of 5-HT₂ Agonists on CR Acquisition and Cognitive Effects in Humans

Drug	Rabbit ED 50^a(μg/kg)	Human dose^b(μg/kg)
LSD	0.8^c	1.0^h
DOM	52^d	50ⁱ
MDMA	500^e	250^j
MDA	800^f	1000^k
BOL	No effect^d,^g	No effect^h

See Table 3 for abbreviations.

Dose of drug required to produce a half maximal enhancement of learning.

Lowest dose required to obtain reliable hallucinations in humans.

Gimpl et al. (1979); ^dHarvey et al. (1982); ^eRomano and Harvey (1994); ^fRomano et al. (1991); ^gRomano et al. (2000); ^hAbramson et al. (1955); Rothlin (1957); Brawley and Duffield (1972); ⁱSnyder et al. (1967); ^jCole and Sumnall (2003); ^kMarquardt et al. (1978); Shulgin (1978); Braun et al. (1980).