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5-HT3-OE mice are less anxious in the elevated plus-maze. Data are mean ± SEM. Black bars, 5-HT3-OE; gray bars, WT. *: A significant difference at P < 0.02 by unpaired t-test. (A) Number of entries into the open arms expressed as a percentage of total arm entries. (B) Time in sec spent in the open arms of the maze. (C) Time (sec) spent in the closed arms of the maze. (D) Time (sec) spent in the center of the maze.
