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Transduction efficiency in mouse ADAS cells with lentiviral-GFP (A,B); Proliferation of floxed Notch1 ADAS cells transduced with lentiviral-Cre recombinase (C), mutant Cre (D), or no virus (E); Quantification of the effect of Notch 1 deletion on clonogenic potential of ADAS spheres from the supernatant or stromal fraction (F). Scale bar in A and B = 55 um; scale bar in C–E = 220 um.
