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. Author manuscript; available in PMC: 2009 Jan 1.
Published in final edited form as: Biochim Biophys Acta. 2007 Oct 2;1780(1):34–40. doi: 10.1016/j.bbagen.2007.09.015

Figure 6. Effect of siRNA, SSL3 on TNF-α secretion: Time-course studies.

Figure 6

Freshly isolated Kupffer cells were cultured for 6 days followed by transfection with 25 nM of the siRNAs. At 24, 48, 72 and 96 h post transfection, TNF-α secretion was induced by LPS for 2 h. Data points indicate TNF-α values which are the means ± S.E. (n=7-8). TNF-α secretion in cells treated with SSL3 was expressed as percent of secretions by those samples treated with NC-siRNA, which had no inhibitory effect on LPS-induced TNF-α secretion (Figs 1-5). **p < 0.01, ***p < 0.005.