Figure 6.
The effects of Aβ plaques on gliogenesis of NPCs in the hippocampus and lateral ventricle of AD-like transgenic mice. A. Representative LacZ, GFAP staining and overlay images in the DG of Bi-Tg mice compared with age-matched pNes-Tg mice controls. No overlay of LacZ and GFAP staining was detected in the hippocampal regions. B. Representative LacZ, GFAP staining and overlay images in the lateral ventricles of Bi-Tg mice compared with age-matched pNes-Tg mice controls. Overlay of LacZ and GFAP staining was detected in the lateral ventricle regions.