Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Model of type I IFN receptor complex and signaling. Ligand binding to the subunits of the type I IFN receptor complex, the IFN-αR2c and the IFN-αR1 chains, initiates the cascade of signal transduction events. All Stats involved in IFN-α signaling are activated through the intracellular domain of the IFN-αR2c chain (see text for details).
