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Incidence and size of polyps
| WT (n=18) | TLR4−/− (n=18) | P value | |
|---|---|---|---|
| Incidence (%) | 100 | 27.8 | 0.027 |
| Tumors/animal (range) | 5.4 ± 1.2 (1 – 17) | 0.4 ± 0.2 (0 – 2) | 0.00016 |
| Tumor size (mm) (range) | 3.6 ± 0.4 (1 – 10) | 1.3 ± 0.3 (0.5 – 1) | 0.02 |
| Percentage of mucosal surface with tumor (range) | 22.6% ± 3.1 (1 – 65) | 4.4% ± 0.6 (1 – 5) | 0.0025 |
