Figure 1.
Control of the respiratory phase of MHV-68 infection by T cells and IFN-γ. The Ig−/− μMT mice were dosed i.p. (27, 29, 32) with the GK1.5 (CD4), 2.43 (CD8), or XMG1.2 (IFN-γ) mAbs, starting 2 days prior to i.n. challenge with 600 pfu of MHV-68. The data are compiled from two experiments, giving final group sizes of 12 mice. The values in the parentheses show the percentage mortality prior to time of sampling on day 21 after virus challenge.