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. 1999 Apr 27;96(9):5141–5146. doi: 10.1073/pnas.96.9.5141

Figure 2.

Figure 2

The development of a sizable, granuloma-like structure depends on the recruitment of NKT cells. (A) Stained sections of the site of injection 7 days after injection of deproteinized cell walls in Jα281−/− mice [objectives: 2.5 (a), 6.3 (b), 40 (c), and oil, 100 (d)], Jα281+/− mice [2.5 (e), 6.3 (f), and 40 (g)], and C57BL/6 MHC class II−/− mice [2.5 (h), 6.3 (i), and 40 (j)]. (Bar = 1 mm.) (B) Vα14 and Vα14-Jα281 usages at the site of injection (Left) and in the lymph nodes (Right) of Jα281−/− (a–d), Jα281+/− (e–h), and C57BL/6 MHC class II−/− mice (i–l). The x and y axes are as in Fig. 1.