Skip to main content
Journal of Bacteriology logoLink to Journal of Bacteriology
. 1979 Jan;137(1):658–660. doi: 10.1128/jb.137.1.658-660.1979

rorA mutation of Escherichia coli K-12 affects the recB subunit of exonuclease V.

B W Glickman
PMCID: PMC218496  PMID: 368034

Abstract

The ATP-dependent nuclease, exonuclease V, of Escherichia coli plays an important role in repair and recombination. The enzyme is composed of two subunits, one of which is the product of the recB and recC genes. In this communication it is shown by mapping and complementation experiments that the rorA mutation, which results in radiation sensitivity but not the loss of recombination ability, is an allele of the recB gene.

Full text

PDF
658

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Glickman B. W., Zwenk H., van Sluis C. A., Rörsch A. The isolation and characterization of an X-ray-sensitive ultraviolet-resistant mutant of Escherichia coli. Biochim Biophys Acta. 1971 Nov 29;254(1):144–154. doi: 10.1016/0005-2787(71)90121-3. [DOI] [PubMed] [Google Scholar]
  2. Glickman W., Guijt N., Morand P. The genetic characterization of lexB32, lexB33 and lexB35 mutations of Escherichia coli: location and complementation pattern for UV resistance. Mol Gen Genet. 1977 Nov 29;157(1):83–89. doi: 10.1007/BF00268690. [DOI] [PubMed] [Google Scholar]
  3. Goldmark P. J., Linn S. Purification and properties of the recBC DNase of Escherichia coli K-12. J Biol Chem. 1972 Mar 25;247(6):1849–1860. [PubMed] [Google Scholar]
  4. Goldmark P. J., Linn S. Purification and properties of the recBC DNase of Escherichia coli K-12. J Biol Chem. 1972 Mar 25;247(6):1849–1860. [PubMed] [Google Scholar]
  5. Willetts N. S., Mount D. W. Genetic analysis of recombination-deficient mutants of Escherichia coli K-12 carrying rec mutations cotransducible with thyA. J Bacteriol. 1969 Nov;100(2):923–934. doi: 10.1128/jb.100.2.923-934.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Bacteriology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES