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. 1999 May 3;145(3):633–642. doi: 10.1083/jcb.145.3.633

Figure 6.

Figure 6

MyHC fiber type is unaffected in MMg mice. Serial sections of EDL (A–F) and soleus (G–L) muscles of wild-type (A–C, G–I) or MMg (D–F, J–L) ∼120 d female mice were stained for A4.951 (slow; A, D, G, and J), A4.74 (2A; B, E, H, and K) and BF-F3 (2B; C, F, I, and L). In both animals, the majority of fibers reacted with a single antibody, confirming that fibers express predominantly a single MyHC isoform. In EDL, rare 2A fibers (arrowhead, A–F) were interspersed with abundant 2B fibers (arrows, A–F). In soleus, the 2A fibers (arrowhead, G–L) were more abundant than in EDL, and most other fibers contained slow type 1 MyHC (arrows, G–L). Note that the apparent increase in size of 2A fibers in MMg EDL was not observed in other animals, and probably reflects individual variation commonly observed. Bar, 100 μm.