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Dendrites in AD were classified by the presence of Aβ deposits and Alz-50 immunoreactivity. (a) An example of a projection of a three-dimensional triple-labeled plaque (Aβ in green, Alz-50 in red, and SMI32 in blue). (b) The area containing the Aβ deposit is outlined to show examples of dendrites. (c) Neurite segments are classified as being outside or inside Aβ deposits and by whether they are Alz-50-immunoreactive. (Bar = 20 μm.)
