Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2001 Apr 2;153(1):35–46. doi: 10.1083/jcb.153.1.35

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2001 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Histologic analysis of articular cartilage of Smad3 ^ex8/ex8 mice. (A and B) Knee joints of P30 wild-type (A) and mutant (B) mice. Notice the increased number of hypertrophic chondrocytes in mutant articular cartilage. (C–F) Knee joints of 4- (C and D) and 7-mo-old (E and F) wild-type (C and E) and mutant (D and F) mice. Arrow points to abnormally accumulated layer of chondrocytes (D). (G–J) Osteophytes found in synovium of 7-mo-old mice. Arrows point to osteophytes, hematoxylin and eosin (G), collagen type II (H), collagen type I (I), and osteocalcin (J) expression in osteophytes. Bar: (A and B) 150 μm; (C–J) 100 μm.