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Paju-ICAM-5 cells induced for neurite outgrowth by ICAM-5. When Paju-WT and Paju-ICAM-5 cells were seeded on immobilized ICAM-5 D1–9-Fc or D1–2-Fc proteins, neurite outgrowth was clearly seen with Paju-ICAM-5 cells, but not with Paju-WT cells. mAb 179B inhibited neurite outgrowth of Paju-ICAM-5 cells, but had no effect on Paju-WT cells. Neither Paju-ICAM-5 nor Paju-WT cells developed neurites on ICAM-1-Fc protein. Bars, 20 μm.
