Table 4.
Study 1a | Study 2a | ||||||
---|---|---|---|---|---|---|---|
Chrom. | Peak location | LODb | 95% CIc | Peak location | LODb | 95% CIc | Combined |
1 | 68 cM | 2.22* | 47–89 cM | 76 cM | 1.40 | 45–94 cM | 2.65* |
2 | 87 cM | 3.5* | 76–107 cM | 92 cM | 2.93* | 80–104 cM | 5.30** |
5 | 37 cM | 2.80* | 17–51 cM | 59 cM | 1.71* | 34–83 cM | 3.35* |
12 | 53 cM | 2.41* | 45–53 cM | 24 cM | 4.86** | 24–33 cM | -- |
13 | 39 cM | 2.93* | 33–41 cM | 33 cM | 3.69** | 22–39 cM | 5.48** |
Study 1: Radcliffe et al. 2004; Study 2: Radcliffe et al., 2006a.
Peak LOD; suggestive (*), significant (**).
95% confidence interval calculated using WinQTLCart (Wang et al. 2006).
LOD scores were combined using Fishers method (Sokal and Rohlf, 1981); scores were not combined for chromosome 12 because the 95% confidence interval for the two QTL did not overlap (Radcliffe et al., 2006a).