. 1999 Apr 27;96(9):5304–5309. doi: 10.1073/pnas.96.9.5304

Table 1.

Changes in rCBF relative to resting PET scans

Maximum thirst								Wet mouth								3 min. after satiation								14 min. after satiation
Segment Hemisphere	Gyrus or region	BA	x	y	z	Cluster size, mm³	Z score	Segment Hemisphere	Gyrus or region	BA	x	y	z	Cluster size, mm³	Z score	Segment Hemisphere	Gyrus or region	BA	x	y	z	Cluster size, mm³	Z score	Segment Hemisphere	Gyrus or region	BA	x	y	z	Cluster size, mm³	Z score
Positive activations
Limbic								Limbic								Limbic								Limbic
L	Ci	24	−6	−10	35	80	3.91	R	Ci	24	16	−12	40	65	3.63	L	I	—	−32	−26	10	63	3.85	R	Ci	24	14	4	38	48	4.17
R	Ci	24	14	−16	42	66	3.57	L	AC	32	−2	36	−3	41	3.44	L	VL	—	20	−22	0	69	3.63	R	PL	—	20	−16	12	50	3.32
L	Ci	24	−10	−4	36	35	3.54	R	PCi	31	8	−50	22	37	3.66	Neostriate								R	VL	—	21	−22	4	78	4.41
L	AC	32	−4	22	37	34	3.28	Neostriate								R	Pu	—	16	6	4	29	3.35	Frontal
L	AC	24	−1	30	10	73	3.23	R	CH	—	8	20	10	38	3.85	Frontal								R	MF	6	13	−18	44	47	3.32
L	P	28	−18	−10	−22	63	5.13	Frontal								R	MF	11	−14	42	−10	43	3.68	Temporal
R	I	13	40	−26	16	60	3.62	L	MF	47	−16	40	−10	71	4.29	Temporal								R	ST	22	51	−38	18	55	3.69
R	PL	—	20	−16	12	46	3.62	R	MF	47	38	36	−6	63	3.63	R	TT	41	36	−26	18	70	3.38	L	ST	38	−47	17	−28	23	3.46
Parietal								R	IF	47	34	31	−4	52	3.49	Occipital								Occipital
R	PG	3	36	−22	38	59	3.62	R	IF	45	51	16	10	49	3.44	R	LG	18	4	−86	−8	66	3.65	R	LG	18	4	−68	−2	87	4.2
L	PG	40	−34	−22	24	30	3.45	R	SC	11	13	22	−12	41	3.33									L	Cu	17	−18	−82	6	36	3.38
Frontal																								Diencephalon–Mesencephalon
L	O	11	−15	24	−10	33	3.37																	L	M	—	−6	−28	−4	34	3.4
Temporal																								R	Po	—	20	−34	−30	64	3.19
R	MT	37	37	−62	7	63	3.82
R	TT	41	40	−26	16	60	3.62
R	MT	21	56	2	−14	50	3.51
Negative activations
Limbic								Limbic								Limbic								Limbic
R	A	—	16	−6	−12	40	−3.75	L	Ci	32	−14	11	36	26	−3.42	L	PCi	30	0	−66	16	67	−3.91	L	PCi	18	−22	−66	8	65	−3.34
R	DM	—	5	−16	16	75	−3.95	L	PCi	29	−10	−44	20	88	−3.67	L	PCi	30	−12	−61	16	82	−3.19	R	DN	—	−5	−10	14	47	−3.39
L	DM	—	−2	−12	14	73	−3.81	R	PCi	31	8	−60	12	80	−3.81	L	I	—	−34	18	1	30	−3.6
								L	P	19	−22	−48	4	62	−3.76
								R	P	36	26	−24	−24	27	−3.67
								R	AN	—	6	−8	14	51	−3.51

Positive activations (increase in rCBF) relative to the control (resting) PET scan with Z score >3.27 or cluster size >60 mm³. The four states scanned were maximum thirst associated with the sense of dryness in mouth; after irrigating the mouth with water but not swallowing (wet mouth); 3 min. after drinking water to satiate thirst; and 14 min. after drinking water to satiate thirst. Data are shown for the cingulate and hippocampal gyrus, amygdala, and thalamus (termed limbic system–Papez); the parietal, frontal, temporal, and occipital lobes; the neostriate; and the diencephalon–mesencephalon. Negative activations (decrease in rCBF) relative to the control PET scan with Z score <−3.27 or cluster size >60 mm³. For the same four states, but only limbic system–Papez deactivations are shown. Ci, cingulate; P, parahippocampal; AC, anterior cingulate; I, insula; PL, posterolateral nucleus of thalamus; PG, postcentral gyrus; MT, midtemporal gyrus; TT, transverse temporal gyrus; A, amygdala; DM, dorsomedial nucleus of thalamus; CH, head of caudate nucleus; MF, medial frontal gyrus; IF, inferior frontal gyrus; SC, subcallosal gyrus; VL, ventrolateral posterior nucleus of thalamus; Pu, putamen; LG, lingual gyrus; Cu, cuneus; M, midbrain; Po, pons; DN, dorsal nucleus of thalamus; PCi, postcingulate; AN, anterior nucleus of thalamus; ST, superior temporal gyrus; O, orbital frontal gyrus.