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. Author manuscript; available in PMC: 2008 Dec 1.
Published in final edited form as: Virus Res. 2007 Jul 2;130(1-2):85–95. doi: 10.1016/j.virusres.2007.05.020

Figure 2. Observed to permuted dinucleotide ratios in HCV RNA ORFs.

Figure 2

A-C There are 16 potential dinucleotides in an ORF (x-axis). The ratio of observed to permuted dinucleotide frequency (y-axis) was calculated (as described in Methods, Method 3) for three interferon-resistant HCV 1b isolates (Enomoto et al., 1995). Ratios below 1.0 correspond to fewer observed dinucleotides than in the average of 100 permuted sequences while ratios above 1.0 correspond to more observed dinucleotides than in the average of 100 permuted ORF sequences.